Endocrine Abstracts

Introduction: Tolosa Hunt syndrome (THS) is described as unilateral orbital pain associated with paresis of one or more of the third, fourth and/or sixth cranial nerves caused by a granulomatous inflammation in the cavernous sinus, superior orbital fissure or orbit. Pituitary gland is rarely involved in this syndrome. Herein we represented a case with hypophysitis with Tolosa Hunt who was operated with the suspicion of pituitary adenoma.Case: A 63-year-o...

Introduction: Association between high thyrotrophin receptor antibodies (TRAb) and relapse of thyroid cancer in Graves’ patients was reported previously. In this study, we aimed to investigate possible relation between TRAb and thyroid malignancies in patients with toxic multinodular (TMNG) and toxic nodular goiter (TNG).Methods: Thyroidectomized patients with a preoperative diagnosis of TMNG, TNG and euthyroid multinodular or nodular goiter (MNG/NG...

Introduction: The predictors of malignancy are important for decision of appropriate management in nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). Our aim was to determine the ultrasonographical, clinical and biochemical predictors of malignancy in these patients.Methods: A total of 427 patients with Bethesda Category III (AUS/FLUS) thyroid nodules were included in this retrospective study. We d...

Introduction: We aimed to determine demographical, hormonal, ultrasonography(US) and cytological features of cases with neck lesions that are located outside the thyroid region and have similar echogenity with thyroid tissue.Method: Neck US reports of patients who underwent fine needle aspiration(FNAB) under US guidance in our clinic in a period of one year were reviewed retrospectively. Lesions having similar echogenity with thyroid tissue and defined a...

Introduction: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) termed as Bethesda Category III constitute 15–30% of thyroid cytology. However, the risk of malignancy in this heterogenous category is estimated as 5–15%. The recent studies has been reported the malignancy rate in the wide range of 6–48%. This causes surgical approach variability between different centers. We aimed to evaluate the initial malignancy rate...

Introduction: Thyroid tumors of uncertain malignant potential (TT-UMP) has been accepted as a subgroup of follicular-patterned thyroid tumors for which benignancy or malignancy cannot be assessed exactly. We aimed to evaluate demographic characteristics, ultrasound (US) findings, and cytological results of patients with TT-UMP and compare these findings with the classical variant of papillary thyroid carcinoma (CV-PTC) and non-encapsulated follicular variant of PTC (NEFV-PTC) ...

Introduction: In recent years, due to the improvements in ultrasonography (US), it has become possible to gain more information about the papillary throid carcinoma (PTC) and papillary tyroid microcarcinoma (PTMC). However, whether PTC and PTMC exhibit the same ultrasonographic features and behave same features is controversial. We aimed to evaluate the patients diagnosed with PTC and PTMC in terms of clinical, ultrasonographical (US) and histopathological features and their r...

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

Background: Differential diagnosis of a thyroid nodule is difficult if it is a follicular lesion. Follicular lesions include follicular adenoma (FA) or a malign neoplasm (follicular cancer (FC) or follicular variant of papillary thyroid carcinoma (FVPTC)). Cytology can’t separate benign from malignant condition in follicular lesions. Differential diagnosis is important because patients often undergo less than ideal interventions, such as a total thyroidectomy for a benign...

Introduction: Hyalinizing trabecular tumor is a very rare neoplasm of thyroid and can be misinterpreted as papillary or medullary cancer in fine needle aspiration biopsy (FNAB).Case report: Multinodular goiter was detected in a 65 years old woman using metformin and L-thyroxine for impaired blood glucose and Hashimoto thyroiditis, respectively. FNAB was performed in two nodules and reported as suspicious for malignancy and benign. She underwent total thy...